The reference site for Fluvastatin

Fluvastatin (INN, trade names Lescol, Canef, Vastin) is a member of the statin drug class, used to treat hypercholesterolemia and to prevent cardiovascular disease.

WHAT IS FLUVASTATIN?

Fluvastatin is an HMG CoA reductase inhibitor. Fluvastatin blocks the production of cholesterol (a type of fat) in the body.

Fluvastatin is used to reduce the amounts of LDL (bad) cholesterol and total cholesterol in your blood. Fluvastatin also reduces the amounts of triglycerides (another type of fat) and apolipoprotein B (a protein needed to make cholesterol) in your blood. These actions are important in reducing the risk of hardening of the arteries, which can lead to heart attacks, stroke, and peripheral vascular disease.

 

Brand Name(s): Lescol; Lescol XL

CAS nº: 93957-54-1

(flew va stah tin)

 

Product Info

The sections below will provide you with more specific information and guidelines related to fluvastatin and its correct use. Please read them carefully.

FDA Information

Fluvastatin is an FDA approved medecine.

In 2003, the U.S. Food and Drug Administration (FDA) approved Lescol®(fluvastatin sodium) and Lescol® XL (fluvastatin sodium) 80 mg extended-release tablets to reduce the risk of undergoing coronary revascularization procedures in patients with coronary heart disease.

NOTE: each year approximately one million patients in the U.S. undergo percutaneous coronary intervention (PCI) procedures, such as angioplasty and stenting, to open blocked arteries. Of those patients, nearly 40 percent will undergo a second procedure or have a heart attack within five years.

Why is this medication prescribed?

Fluvastatin is an HMG CoA reductase inhibitor. Fluvastatin blocks the production of cholesterol (a type of fat) in the body.

Fluvastatin is used to reduce the amounts of LDL (bad) cholesterol and total cholesterol in your blood. Fluvastatin also reduces the amounts of triglycerides (another type of fat) and apolipoprotein B (a protein needed to make cholesterol) in your blood. These actions are important in reducing the risk of hardening of the arteries, which can lead to heart attacks, stroke, and peripheral vascular disease.

Other uses for this medicine

Fluvastatin is also used to slow down the hardening of the arteries in people who already have coronary heart disease caused by high cholesterol levels.

However, It is important that you talk to your doctor about the possible risks of using this drug for your particular condition.

Dosage and using this medicine

Fluvastatin comes as a capsule and an extended-release (long-acting) tablet to take by mouth. The capsule usually is taken once a day at bedtime or twice a day. The extended-release tablet usually is taken once a day at bedtime.

Take fluvastatin exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

For the greatest effect, fluvastatin is usually taken at bedtime or with an evening meal.

Fluvastatin may also be taken twice daily. Follow your doctor’s directions.

Do not crush, chew, or break the extended-release tablets (Lescol XL®). Swallow them whole.

Your doctor may want to monitor your liver function with blood tests before starting treatment with fluvastatin and at twelve weeks after both the start of your treatment and any increase in dose. Depending on the results of these tests, your doctor can determine how much monitoring you will require.

Eat a low-fat, low-cholesterol diet. To realize beneficial effects from fluvastatin, avoid fatty, high-cholesterol foods.

It is important to take fluvastatin regularly to get the most benefit.

Do not stop taking fluvastatin without first talking to your doctor. Fluvastatin may need to be taken on a long-term basis for the treatment of high cholesterol.

Your doctor may want you to have blood tests or other medical evaluations during treatment with fluvastatin to monitor progress and side effects.

What special precautions should I follow?

BEFORE TAKING FLUVASTATIN:

Tell your doctor if you have kidney disease, drink alcoholic beverages, have a chronic muscular disease, or have a blood disorder; liver disease. You may not be able to take fluvastatin, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Fluvastatin is in the FDA pregnancy category X. This means that fluvastatin is known to cause birth defects if it is taken during pregnancy. Do not take fluvastatin if you are pregnant or could become pregnant during treatment.

Fluvastatin passes into breast milk and may be harmful to a nursing infant. Do not take fluvastatin without first talking to your doctor if you are breast-feeding a baby.

Alcohol and fluvastatin can both be damaging to the liver. Alcohol should be used only in moderation. Discuss the use of alcohol with your doctor so that the potential for liver problems can be determined.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Possible side effects from fluvastatin include:

abdominal pain
stomach cramps
flatulence (gas)
indigestion

Tell your doctor if any of these symptoms are severe or do not go away:

bloating
nausea
stomach upset
heartburn
constipation
diarrhea
cough
headache
insomnia

If you experience any of the following symptoms, call your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue or face or hives)
decreased urine or rust-colored urine
blurred vision

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of an emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

nausea
diarrhea
stomach distress
indigestion

Product Images

PICTURES OF FLUVASTATIN PILLS

Below you will find images and specific information on the principal types of fluvastatin that exist, including their respective brand name(s), strength, inscription codes and manufacturers.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

Name: LESCOL®
Strength(s): 40 MG
Imprint: 40 LESCOL
Manufacturer: NOVARTIS

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